针刺治疗60例肿瘤伴发焦虑抑郁患者的临床研究

Acupuncture Treatment for 60 Patients with Anxiety and Depression

[目的]观察针刺对肿瘤相关性焦虑、抑郁及生活质量的临床疗效。[方法]将60例肿瘤患者随机分为针刺组和西药组,针刺组针刺合谷、内关、太冲、阳陵泉等穴位;西药组予盐酸舍曲林片(左洛复)治疗,2组均连续治疗4周。观察两组患者生活质量核心问卷(Quality of Life QuestionnaireCore 30,QLQ-C30)、汉密尔顿焦虑量表(Hamilton Anxiety Scale,HAMA)和抑郁量表(Hamilton Depression Scale,HAMD)评分的变化情况。[结果]治疗后,两组与治疗前相比,HAMA及HAMD评分均明显降低(P<0.05),且治疗后4周,西药组改善焦虑抑郁程度及其在情绪功能的单项评分显著优于针刺组(P<0.05),但针刺组治疗后4周在疲乏、恶心呕吐、失眠、食欲减退、角色功能及总体生活质量单项评分改善明显优于西药组(P<0.05)。[结论]针刺在提高肿瘤相关性焦虑、抑郁的临床疗效的同时,能帮助改善肿瘤患者常见伴发症状并提高其生活质量,可在临床推广运用。

[Objective]To observe the acupuncture correlation with the clinical curative effect of anxiety, depression and quality of life.[Methods] The 60 patients with tumor were randomly divided into acupuncture group and western medicine group, acupuncture group acupunetured Neiguan（P6）, Taichong（Liv3）,Yanglingquan（SP9） and other acupuncture points .The western medicine group was treated with Sertralinc Hydrochloride tablets（Zoloft） and 2 groups were treated for 4 weeks consecutively. The changes in the quality of life of the two groups（QLQ-C30）,Hamihon anxiety scale（HAMA） and depression seale（HAMD） were observed. [Resuhs]Two groups were compared with before treatment, HAMA and HAMD scores were significantly lower（P〈 0.05）, and 4 weeks ＇after treatment, western medicine improved the degree of anxiety depression and score of emotional function was significantly better than that of acupuncture group（P〈0.05）,but after the acupuncture treatment group 4 weeks fatigue, nausea and vomiting, insomnia, loss of appetite, role function and overall quality of life of individual score improved significantly better than western medicine group（P〈0.05）.[Conelusion]The clinical effect of aeupuncture on improving tumor related anxiety and depression is not as good as the improvement of Western medicine, but it can help to improve the common symptoms of cancer patients and improve the quality of life, and can be used in clinical application.