痛风合并上消化道出血的相关危险因素分析

Analysis of relevant risk factors of gout with upper gastrointestinal hemorrhage

目的:探讨痛风患者合并上消化道出血的危险因素。方法:我院收治的痛风合并上消化道出血患者89例作为病例组,150例无上消化道出血的痛风患者作为对照组,采用单因素和二元Logistic回归分析痛风患者合并上消化道出血的相关危险因素。结果:冠心病病史、胃病史、饮酒史在痛风合并上消化道出血中比值比(OR)分别为3.31,95%CI(1.12~9.18),3.49,95%CI(1.31~9.29)和2.23,95%CI(1.16~4.30),具有统计学意义(P<0.05)。结论:冠心病病史、胃病史以及饮酒史是痛风合并上消化道出血的独立危险因素。

Objective： To explore the risk factors of gout combined with upper gastrointestinal bleeding.Methods： 89 gout patients with upper gastrointestinal hemorrhage and 150 gout patients without upper gastrointestinal hemorrhage were selected as case group and control group. Univariate and binary logistic regression were used to analyze the risk factors of upper gastrointestinal hemorrhage in gout patients.Results： The ORs of coronary heart disease history,gastric disease history and drinking history in gout complicated with upper gastrointestinal bleeding were 3. 31,95% CI（ 1. 12 ~ 9. 18）,3. 49,95% CI（ 1.31~ 9.29） and 2.23,95% CI（ 1.16~4.30）,they were statistically significant（ P〈0.05）. Conclusion：The history of coronary heart disease,gastric disease and alcohol drinking is independent risk factors for gout complicated with upper gastrointestinal bleeding.