心脉隆联合阿托伐他汀治疗慢性心衰患者的疗效观察

Effect of Xinmailong combined with atorvastatin on patients with chronic heart failure

目的:观察心脉隆联合阿托伐他汀对慢性心衰患者血浆BNP水平及心功能的影响。方法:92例慢性心衰患者随机分为两组,对照组给予阿托伐他汀治疗,观察组在对照组基础上联合心脉隆治疗。比较两组疗效、血浆CRP和BNP水平及心功能。结果:治疗后,观察组总有效率、LVEF高于对照组,CRP、BNP、LVDD低于对照组,差异均具有统计学意义(P<0.05)。结论:心脉隆联合阿托伐他汀治疗能有效改善慢性心衰患者心功能,降低血清BNP,提高治疗效果。

Objective： To observe the effect of Xinmailong combined with atorvastatin on plasma BNP level and cardiac function in patients with chronic heart failure. Methods： 92 patients with chronic heart failure were divided into two groups randomly. The control group was treated with atorvastatin,and the observation group was treated with Xinmailong on the basis of the control group. The efficacy,plasma CRP and BNP levels and cardiac function were compared between the two groups. Results： After treatment,the total effective rate and the LVEF of the observation group were higher than those of the control group,while the LVDD,CRP and BNP were lower than those in the control group. The differences were statistically significant（ P〈0.05）. Conclusion： Xinmailong combined with atorvastatin can effectively improve cardiac function,reduce serum BNP and improve therapeutic effect in patients with chronic heart failure.