不同产区板蓝根药材质量考察

Study on quality of Isatidis Radix in different production areas

对内蒙古、陕西、甘肃、河北、河南、山东、黑龙江7个产地板蓝根进行质量比较,测定了水分、灰分、浸出物和(R,S)-告依春含量。结果表明,不同产区的板蓝根水分含量在8. 86%～11. 72%,陕西产地的含量最低;总灰分含量在3. 55%～7. 00%,山东产地的含量最低;酸不溶性灰分含量0. 14%～0. 62%,山东产地的含量最低;醇溶性浸出物含量在29. 99%～43. 71%,陕西产地的含量最高; HPLC含量测定结果显示(R,S)-告依春含量在0. 444～1. 042 mg/g,河南产地的含量最高。各产地的板蓝根药材的水分、灰分、浸出物和(R,S)-告依春含量均符合标准,实验结果对于农业生产和临床用药有一定的指导意义。

The contents of water, ash, leachate and （R, S）-goitrin in Isatidis Radix from 7 regions such as Inner Mongolia, Shaanxi, Gansu, Hebei, Henan, Shandong, and Heilongjiang were determined and compared. The results showed that the water content of Isatidis Radix in different producing areas ranged from 8.86% to 11.72%, and the lowest in Shaanxi.The total ash content was between 3.55% and ？.00%, and the content of ash in Shandong was the lowest.The acid-insoluble ash content was 0.]4% - 0.62%, the content of acid-insoluble ash in Shandong was the lowest.The content of alcohol-soluble extract was from 29.99% to 43.71%, the content of Isatidis Radix extract in Shaanxi was the highest.The result of HPLC content measurement showed that the content of （ R, S）-goitrin was 0.444 - 0.042 mg/g, （ R, S）-goitrin in the Isatidis Radix from Henan produced was the highest content. The water, ash, leachate and （R, S）-Goitrin content of Isatidis Radix in each producing area met the standards. The experimental results have certain guiding significance for agricultural production and clinical drug use.