成都市疾病预防控制中心健康检查者脂肪肝阳性率及相关因素分析

Analysis of fatty liver positive rate and related factors in physical examinees of Chengdu Center for Disease Control and Prevention

目的探讨和研究972例健康检查者的脂肪肝阳性率及其相关因素。方法对2016年1~12月成都市疾病预防控制中心972例健康检查者进行研究,按照是否检出脂肪肝阳性将其分为脂肪肝组和非脂肪肝组,分析体检者一般资料、实验室检查及腹部B超检查结果,应用SPSS 19.0软件进行统计分析。结果 972例健康检查者中检出脂肪肝174例,阳性率为17.901%,其中,男性脂肪肝的阳性率高于女性,差异有统计学意义(χ2=46.100,P<0.05)。脂肪肝组年龄、空腹血糖(FPG)、总胆固醇(TC)、三酰甘油(TG)、丙氨酸氨基转移酶(ALT)、γ-谷氨酰转移酶(GGT)水平、饮酒者比例、吸烟者比例均高于非脂肪肝组,差异有统计学意义(P<0.05)。二分类非条件Logistic回归分析显示,高龄、男性、FPG、TC、TG和ALT与脂肪肝的发生相关,是脂肪肝的危险因素(P<0.05)。结论高龄、男性、FPG、TC、TG、ALT与脂肪肝的发生有着密切的关系,是脂肪肝的危险因素。

Objective To explore and study the positive rate of fatty liver and its related factors in 972 physical exam- inees. Methods A study was carried out on 972 physical examinees in Chengdu Center for Disease Control and Preven- tion from January to December 2016, the physical examinees were divided into fatty liver group and non fatty liver group according whether they were fatty liver positive or not. The results of general information, laboratory examination and abdominal B ultrasonic examination were analyzed, and SPSS 19.0 software was used for statistical analysis. Re- sults Among the 972 cases, 174 cases of fatty liver were detected, the positive rate was 17.901%, of which, the fatty liver positive rate of male was higher than that of female, the difference was statistically significant （χ^2 = 46.100,P 〈 0.05）. The age, levels of fasting plasma glucose （FPG）, total cholesterol （TC）, triglyceride （TG）, alanine aminotransferase （ALT）, gamma glutamyl transferase （GGT） and proportions of alcohol and smoking of fatty liver group were higher than those of non fatty liver group, the differences were statistically significant （P 〈 0.05）. The two classification uncondi- tional Logistic regression analysis showed that advanced age, male, FPG, TC, TG and ALT were associated with the occur- rence of fatty liver, and they were risk factors of fatty liver （P 〈 0.05）. Conclusion Advanced age, male, FPG, TC, TG and ALT are closely related to the occurrence of fatty liver, and they are the risk factors of fatty liver.