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联合检测血清IL-37、PCT与Hs-CRP对支气管哮喘患者急性发作的临床意义 被引量:12

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摘要 目的探究联合检测血清IL-37、PCT与Hs-CRP对支气管哮喘患者急性发作的临床意义。方法选取我院2016年6月-2017年6月收治确诊为支气管哮喘急性期患者69例,所有患者均在入院时检测血清IL-37、PCT与Hs-CRP水平,再根据痰细菌定量培养结果,将痰中下呼吸道潜在病原菌(ppm)浓度≥107cfu/ml的患者分为感染组(n=38),浓度<107cfu/ml的患者分为未感染组(n=31),比较两组患者血清IL-37、PCT与Hs-CRP水平,并采用受试者测试工作曲线(ROC)分析血清IL-37、PCT与Hs-CRP对支气管哮喘患者细菌感染的预测价值。结果感染组患者血清PCT、Hs-CRP水平明显高于未感染组的(P<0.05),而感染组患者血清IL-37则明显低于未感染组的(P<0.05),ROC曲线显示血清IL-37、PCT与Hs-CRP联合检测支气管哮喘患者患有明显细菌感染的敏感度为89.47%,特异度为93.55%。结论支气管哮喘急性发作期患者合并细菌感染后血清IL-37、PCT与Hs-CRP水平明显异于未感染的患者,联合检测支气管哮喘患者血清IL-37、PCT与Hs-CRP有助于调整患者抗生素治疗方案。
作者 罗东娟
出处 《实验与检验医学》 CAS 2018年第5期770-772,共3页 Experimental and Laboratory Medicine
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