保乳手术和改良根治手术在乳腺癌患者临床治疗的效果

The effect of breast-conserving surgery and modified radical mastectomy in breast cancer patients

目的探讨保乳手术和改良根治手术在乳腺癌患者临床治疗的效果。方法将2010年12月～2016年12月我院收治的1000例乳腺癌患者根据手术方法分组。对照组进行改良根治手术治疗,观察组行保乳手术治疗。比较两组乳腺癌手术治疗总有效率、手术平均实施时间、平均手术引流量、手术过程总出血量、术后总住院治疗时间、手术前后患者生活质量量表SF-36分值、手术不良事件发生情况。结果观察组乳腺癌手术治疗总有效率高于对照组(P<0.05);观察组手术平均实施时间、平均手术引流量、手术过程总出血量、术后总住院治疗时间优于对照组(P<0.05);手术前两组生活质量量表SF-36分值相近(P>0.05);手术后观察组生活质量量表SF-36分值优于对照组(P<0.05)。观察组手术不良事件少于对照组(P<0.05)。结论乳腺癌患者行保乳手术疗效肯定,效果优于改良根治手术,可更地好保留乳房外观,减轻形体缺失和对患者的影响,减少手术创伤和并发症,从而更好地改善患者术后的生活质量。

Objective To investigate the effect of breast-conserving surgery and modified radical mastectomy in breast cancer patients. Methods A total of 1000 patients with breast cancer from December 2010 to December 2016 were reviewed and grouped according to surgical methods. The control group underwent modified radical mastectomy and the observation group underwent breast-conserving surgery. The total effective rate of surgical treatment, the average time of surgical operation, average surgical drainage volume, total blood loss during the surgical procedure, and total postoperative hospitalization time; the score of the quality of life scale SF-36 before and after surgery and the occurrence of adverse events were compared between the two groups. Results The total effective rate of surgical treatment for breast cancer in the observation group was higher than that in the control group（P〈0.05）. The mean time for surgical operation, mean surgical drainage, total blood loss during the operation, and postoperative total hospital stay were significantly better in the observation group those that in the control group（P〈0.05）. The scores of the two groups of quality of life scale SF-36 were similar before the surgery（P〉0.05）. After the surgery, the score of quality of life scale SF-36 in the observation group was better than that in the control group（P〈0.05）. The number of adverse events in the observation group was less than that in the control group（P〈0.05）. Conclusion Breast-conserving surgery has positive curative effect on breast cancer patients and its effect is better than that of modified radical mastectomy. The former can better preserve the appearance of the breast, reduce the loss of body and the impact on patients, and reduce the surgical trauma and complications, so as to better improve the postoperative patients＇ quality of life.