急诊内镜下硬化剂治疗肝硬化合并上消化道出血的疗效分析

Analysis of Curative Effect of Hardener under the Emergency Endoscopy in Treatment of Cirrhosis Combined with Upper Gastrointestinal Hemorrhage

目的观察急诊内镜下应用硬化剂治疗肝硬化合并上消化道出血的疗效分析。方法选取2016年1月—2018年1月该院急诊收治的患者100例,采用随机数字表法分为观察组50例和对照组50例,对照组采用常规内科治疗,观察组在内镜下注射聚桂醇治疗,观察其治疗疗效、止血情况及不良反应等情况。结果观察组治疗后总有效率90%,对照组治疗后总有效率70%,两组相比差异有统计学意义(χ~2=6.25,P=0.01),观察组再出血率6%,对照组再出血率20%,两组相比差异有统计学意义(χ~2=4.33,P=0.037)。另外观察组在止血时间、肠鸣音正常时间、输血量及住院天数情况较对照组有明显改善,差异有统计学意义(P<0.05),且并发症较少。结论急诊内镜下应用硬化剂治疗肝硬化合并上消化道出血疗效较佳,值得临床推广。

Objective To observe the curative effect of hardener under the emergency endoscopy in treatment of cirrhosis combined with upper gastrointestinal hemorrhage. Methods 100 cases of emergency patients in our hospital from January 2016 to January 2018 were selected and randomly divided into two groups with 50 cases in each, the control group used the routine therapy in the department of internal medicine, while the observation group used the endoscopic injection of lauromacrogol, and the curative effect, hemostasis and adverse reactions were observed. Results The total effective rate in the observation group and in the control group was respectively 90% and 70%, and the difference was statistically significant（χ~2=6.25, P=0.01）, and the rehemorrhage rate in the observation group and in the control group was respectively 6% and 20%, and the difference between groups was statistically significant（ χ~2=4.33, P=0.037）. Besides, the hemostasis time, bowel sound normal time, blood transfusion amount and length of stay in the observation group were obviously improved, and the differences were statistically significant（P0.05）, with few complications. Conclusion The curative effect of hardener under the emergency endoscopy in treatment of cirrhosis combined with upper gastrointestinal hemorrhage is better, which is worth clinical promotion.