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奥美拉唑联合抗血小板治疗对冠心病PCI术病人预后的影响 被引量:7

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摘要 目的观察奥美拉唑联合抗血小板治疗对冠心病病人经皮冠状动脉介入(PCI)治疗预后的影响。方法选取我院2014年4月—2016年8月收治的冠心病PCI治疗病人80例,随机分为对照组及观察组,各40例。两组病人均使用阿司匹林及氯吡格雷行双抗血小板治疗,观察组在此基础上加用奥美拉唑。比较两组病人血小板聚集率及心血管事件、消化道出血、心脏急症发生情况。结果治疗后两组血小板聚集率均下降,两组比较差异无统计学意义(P>0.05)。观察组心肌再梗死、支架内血栓、靶血管重建等心血管事件发生率分别为5.00%、2.50%、2.50%,与对照组的2.50%、5.00%、2.50%比较,差异无统计学意义(P>0.05)。观察组消化道出血发生率为2.50%,低于对照组的20.00%,差异有统计学意义(P <0.05)。观察组心绞痛频繁发作、因心力衰竭再次住院、急性心肌梗死等心脏相关急症发生率分别为7.50%、2.50%、5.00%,与对照组的12.50%、7.50%、7.50%比较,差异均无统计学意义(P>0.05)。结论奥美拉唑联合抗血小板治疗可明显减少冠心病病人PCI术后消化道出血情况,对血小板聚集率不会产生影响,心血管事件未增加,心脏急症发生少,临床治疗效果显著。
作者 田家齐
出处 《中西医结合心脑血管病杂志》 2018年第18期2679-2681,共3页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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