术后认知功能障碍的研究进展

Recent advances in the study of post-operative cognitive dysfunction

术后认知功能障碍(POCD)是老年患者麻醉手术后的常见并发症,主要表现为人格、社交能力及认知能力的改变。随着我国老龄化社会的到来,医院就诊的老年患者也相对增加,越来越多的研究开始关注POCD,然而目前关于POCD的发生机制并不清楚。因此,该文总结了POCD近年来的研究进展,对其可能机制和危险因素进行综述,为临床麻醉方案的实施和POCD的防治提供参考。

Post-operative cognitive dysfunction（ POCD） is a common complication in elderly patients after anesthesia and operation. It is mainly manifested by changes in personality,social skills and cognitive abilities. With the advent of an aging society,the number of elderly patients has also relatively increased,more and more researches have begun to focus on the problem of POCD. However,the current mechanism of POCD is unclear. This article summarizes recent progress in POCD research,reviews its possible mechanisms and risk factors,to provide reference for clinical anesthesia and POCD prevention.