硫化氢对线粒体损伤后氧化呼吸链影响的研究进展

Advances in studies on the effect of hydrogen sulfide on oxidative respiratory chain after mitochondrial injury

探讨硫化氢对线粒体损伤后氧化呼吸链的影响。已有研究证实,硫化氢在线粒体损伤后有保护氧化呼吸链,稳定细胞色素C氧化酶活性及氧化磷酸化反应的作用,进而保证ATP的生成。通过对比国内相关研究,就硫化氢对线粒体损伤后氧化呼吸链的影响,归纳其作用机制,为今后硫化氢的进一步研究提供相关的理论基础。

To investigate the effect of hydrogen sulfide on oxidative respiratory chain after mitochondrial injury. Studies have confirmed that hydrogen sulfide protects the oxidative respiratory chain after mitochondrial injury, stabilizing cytochrome C oxidase activity and oxidative phosphorylation, thereby ensuring the production of ATP. By comparing the related studies in China, the effect of hydrogen sulfide on the oxidative respiratory chain after mitoehondrial injury and its meehanism of action was summarized in this paper, providing a theoretical basis for the further study of hydrogen sulfide in the future.