富血小板血浆引导骨再生在上颌美学区单牙种植修复中的应用研究

Application of Platelet Rich Plasma Guided Bone Regeneration in Single-tooth Implant Restoration in Maxillary Aesthetic Area

目的:研究富血小板血浆引导骨再生在上颌美学区单牙种植修复中的应用效果。方法:选择2013年1月-2017年1月行上颌美学区单牙种植修复的225例患者为研究对象,根据是否混有富血小板血浆将其分为观察组与对照组,分别给予富血小板血浆引导骨再生、无混有富血小板血浆干预,评价各组种植修复的成功率、骨吸收、红色美学指数(PES)、白色美学指数(WES)及主观满意度情况。结果:两组均成功种植修复,两组骨吸收、WES评分比较无明显差异(P>0.05);观察组种植修复即刻、修复后6个月、12个月PES评分及种植修复后12个月附着高度、整体美观评分均显著高于对照组,差异有统计学意义(P<0.05)。结论:富血小板血浆引导骨再生效果明显,能有效促进骨再生及修复,且美学效果良好。

Objective To study the application effects of platelet rich plasma guided bone regeneration in single-tooth implant restoration in maxillary aesthetic area. Methods According to the use of mixed platelet rich plasma, 225 patients who underwent tooth implant restoration in maxillary aesthetic area from January 2013 to January 2017 were divided into the observation group and the control group. The two groups were given platelet rich plasma guided bone regeneration and intervention without platelet rich plasma respectively. The success rate of restoration, bone resorption, pink esthetics index （PES）, white aesthetic index （WES） and subjective satisfaction were evaluated. Results The implant restoration in the two groups was successful, and there were no significant differences in bone resorption and WES scores between the two groups （P〉0.05）. PES scores of the observation group at implant restoration, at 6 and 12 months after implant restoration, the attachment height and the overall appearance scores at 12 months after implant restoration were significantly higher than those in the control group （P〈0.05）. Conclusion Platelet rich plasma can significantly promote bone regeneration and repair, and the aesthetic effect is good.