李达中医药介入造血干细胞围移植期思路与经验

Exploration and experience of traditional Chinese medicine intervention in hematopoietic stem cell preitransplantation by LI Da

因环境恶化等原因,血液系统疾病发病率呈增高趋势,造血干细胞移植是最有希望根治血液病的方法之一,但干细胞来源困难、移植中并发症、移植后移植物抗宿主病(GVHD)等多方面因素极大限制了干细胞移植应用、影响其疗效及移植后生活质量,中医药序贯治疗介入围移植期有优势与特色。文章介绍李达教授多年临证探索的关于中医药介入围移植期的思路与方法以及中药介入增效减毒的经验。

Due to many causes such as environmental deterioration, the incidence of blood system diseases is increasing. Hematopoietic stem cell transplantation is one of the most promising methods to cure hematopathy, but the difficulty in source of stem ceils, complications in transplantation, graft-versus-host disease （GVHD） after transplantation and other factors greatly limits the application of stern cell transplantation, affected its curative effect and quality of life after transplantation. The sequential therapy of TCM has advantages and characteristics in interventional transplantation. This paper introduces the thoughts and methods of professor LI Da＇s years of research on TCM intervention in the peritransplantation and his experience of Chinese medicine intervention in enhancing effect and reducing toxicity.