不同时间窗及疗程的高压氧治疗对急性脑梗死临床效果分析

Clinical effects of hyperbaric oxygen therapy with different time windows and courses on acute cerebral infarction

目的:观察对于急性脑梗死采取不同时间窗及疗程的高压氧治疗的临床效果分析。方法:选择急性脑梗死患者126例,随机数字法分成采取不同时间窗及疗程的7组,每组18例。将7组患者神经功能缺损评分NIHSS、生活能力评分ADL、脑损伤程度进行对照。结果:NIHSS评分由低至高为C组、B组、E组、D组、G组、F组、A组,ADL评分由高至低为C组、B组、E组、D组、G组、F组、A组,脑损伤程度由轻到重依次为C组、B组、E组、D组、G组、F组、A组,差异具有统计学意义(P <0. 01)。结论:对于急性脑梗死患者采取高压氧治疗疗效明显优于常规内科治疗,而在高压氧治疗中,对急性病发12 h内的时间窗进行疗程为40 d有效的高压氧治疗可明显改善患者神经功能缺损评分,提高患者生活能力,改善脑缺损程度,效果理想。

Objective To observe the clinical effect of hyperbaric oxygen therapy on acute cerebral infarction with different time windows and courses. Method 126 patients with acute cerebral infarction were selected, according to the random number method,they was divided into 7 groups of 18 cases in each group of 7 groups with different time window and course of treat- ment. The neurological deficit score NIHSS, life ability score ADL and brain injury- degree of the 7 groups were compared. Results The scores of NIHSS were in group C,group B,group E,group D,group G,F group and A group,and ADL score from high to low to C group, B group, E group, D group, G group, F group and A group. The degree of brain injury- ranged from hight to heavy in grou C, group B, group E, group D, group G, group F, group A （P 〈 0. 01 ）. Conclusion the curative effect of hyperbaric oxygen therapy for patients with acute cerebral infarction is obviously better than that of conventional medicine. In the treatment of hyper- baric oxygen therapy, the time window of 12 h in the treatment of acute disease is 40 d effective hyperbaric oxygen therapy, which can obviously improve the score of nerve function defect, improve the living ability of the patients, improve the degree of brain de- fect and effect the degree of brain defect. The fruit is ideal.