静电纺丝工艺在医用敷料研制中的应用

Application in manufacture of wound dressing by electrospinning

静电纺丝工艺是一种简便且高效制备纳米纤维的方法，其纤维膜具有比表面积大、孔隙率高等特点，可通过在纺丝过程中加入不同添加剂来制备功能性纳米纤维，在生物医用领域表现出巨大的潜力。随着对医用敷料性能要求的提高，利用静电纺丝工艺制备医用敷料在近年来引起学者的关注。综述了静电纺丝工艺的原理及其在制备医用敷料上的性能优势，介绍了静电纺丝工艺在体外伤口护理医用敷料、药物释放医用敷料及皮肤再生医用敷料方面的应用，为静电纺丝工艺在医用敷料研制中的应用提供参考。

Electrospinning is a simple and effective method to produce nanofibers, and the membrane of the fibers has many advantages such as large specifc surface areas and high porosity. In addition, the functional nanofibers can be prepared by the addition of different additives during the process of electrospinning. It shows great potential in the field of biomedical. With the improvement of medical dressing performance requirements, wound dressing prepared by the method of electrospinning has drawn special attention recently. The principle of electrospinning and its performance advantages are illustrated. The applications of the electrostatic spinning technology in wound care, drug release and skin regeneration wound dressing are introduced. The research is expected to provide beneficial references for clinical application of wound dressings.