四磨汤治疗肺癌患者应用羟考酮致便秘分析

Analysis on Simo Decoction in the Treatment of Constipation induced by Oxycodone Acetaminophen in Lung Cancer Patients

目的分析讨论四磨汤治疗肺癌患者应用盐酸羟考酮缓释片致便秘的疗效。方法选取山西省肿瘤医院2016年6月—2018年1月收治的应用盐酸羟考酮缓释片致便秘患者肺癌患者中的80例,按照其入院号随机分为对照组和治疗组,每组40例患者,对照组使用乳果糖口服液进行治疗,治疗组使用四磨汤治疗,经过治疗后,比较分析2组患者的治疗效果、脑肽含量变化。结果在治疗后,2组患者都有一定的治疗效果,但是治疗组优于对照组,治疗组的治疗总有效率高于对照组,治疗组Gas和VIP含量低于对照组,MTL含量高于对照组,差异具有统计学意义,P<0.05。结论四磨汤治疗肺癌患者应用盐酸羟考酮缓释片致便秘的治疗效果较好,能够改善患者的便秘情况,具有很高的临床应用价值。

Objective To analyze and discuss the effect of Simo decoction on constipation caused by oxycodone hydrochloride prolonged-release tablets in patients with lung cancer. Methods 80 cases of lung cancer patients with constipation caused by oxycodone hydrochloride prolongedrelease tablets in Shanxi cancer hospital from June 2016 to January 2018 were randomly divided into control group and treatment group according to their admission number,with 40 patients in each group. The control group was treated with lactulose oral liquid,and the treatment group was treated with Simo decoction. After treatment,the therapeutic effects and brain peptide contents of the two groups were compared. Results After treatment,the two groups had a certain therapeutic effect,but the treatment group was superior to the control group. The total effective rate of the treatment group was higher than that of the control group. The content of Gas and VIP in the treatment group was lower than the control group,and the content of MTL of the treatment group was higher than that of the control group. The difference was statistically significant P 〈 0. 05. Conclusion The therapeutic effect of Simon decoction on constipation caused by Oxycodone hydrochloride prolongedrelease tablets in patients with lung cancer is better,which can improve the constipation of patients with high clinical value.