乳腺癌风险预测模型研究进展

Research Progress in the Risk Prediction Models of Breast Cancer

乳腺癌是女性最常见的恶性肿瘤之一,发病率呈逐年上升趋势,疾病负担日益加重,已成为严重危害全球女性生命健康的重要疾病。因此,发展简单有效的乳腺癌风险预测工具已经成为乳腺癌预防研究的重点。乳腺癌风险预测模型可以通过计算预测未来一定时间内乳腺癌的发病率。目前,已有多个国家和地区基于不同的基因及流行病学资料建立了不同人群的乳腺癌风险评估模型。这些模型的应用为临床诊断和防治提供了依据,提高了公众对疾病危险因素的认识,有利于卫生资源合理分配。

Breast cancer is one of the most common types of cancer among females with increasing incidence and disease burden, which is a serious threat to life and health of women worldwide. Therefore, developing a simple and effective tool to predict the risk of breast cancer has become the focus of the breast cancer prevention research. Breast cancer risk prediction model can predict the probability of breast cancer within a certain time in the future by calculation. So far, many countries have established breast cancer risk assessment models based on different genetic and epidemiological data. The application of these models is beneficial to the clinical diagnosis and treatment, which raises the public awareness of the risk and helps to the rational distribution of health resources.