鬼箭羽中的1个新西松烷型二萜

A new cembranoid diterpene from twigs of Euonymus alatus

目的研究鬼箭羽(卫矛Euonymus alatus带栓翅的枝条)中的化学成分。方法采用多种柱色谱技术对鬼箭羽95%乙醇提取物进行分离纯化,根据理化性质和波谱数据进行结构鉴定。结果从鬼箭羽提取物中分离得到了3个化合物,分别鉴定为(1S,2S,7E,11R,12S)-2,11-dihydroxy-1,12-oxidocembra-4(18),7(8)-diene(1)、hemerocallal A(2)、桦木酸甲酯(3)。结论化合物1为新的西松烷型二萜,命名为鬼箭羽二萜A,化合物2和3为首次从鬼箭羽中分离得到。

Objective To study the chemical constituents from the twigs of Euonymus alatus. Methods Compounds were isolated and purified by a combination of various chromatographic techniques, and their structures were elucidated by physiochemical property and spectral analysis. Results Three compounds were obtained from 95% ethanol extract of the twigs of E. alatus and identified as（1S,2S,7E,11R,12S）-2,11-dihydroxy-1,12-oxidocembra-4（18）,7（8）-diene（1）, hemerocallal A（2）, and betulinic acid methyl ester（3）. Conclusion Compound 1 is a new cembranoid diterpene and named euonymuditerpene A, and compounds 2 and 3 are isolated from the twigs of Euonymus alatus for the first time.