基于CT数据的颌骨支架材料有限元分析及3D打印模型研究

Research on Finite Element Analysis of Jaw Bone Scaffold Materials and the 3D Printing Model Based on CT Datas

本研究基于CT数据对颌骨支架材料进行有限元分析及3D打印模型研究,为了进一步确定CT技术与3D打印技术在骨组织构建工程的可行性,同时探讨构建骨组织支架材料工程的技术问题,本研究利用骨缺损区域的CT数据进行三维构建,对武汉市第一医院颌面外科颌骨囊肿患者的颌骨缺损区进行CT扫描,再将DICOM数据导入Mimics中,根据CT数据对颌骨缺损部分进行三维建模。支架材料内部形态基于Pro/E软件设计3种不同的支架-立方体结构、蜂窝结构、仿生骨结构。设置支架材料负载为90 N,泊松比为0.3,弹性模量为11 Gpa,地面为完全约束,对支架结构的形变及应力进行有限元分析。构建的支架结构导入Magics中,输出STL格式,连接3D打印机制备支架的三维模型实体模型。本实验发现：（1）使用3D打印技术制得三种支架实体模型,支架材料模型外部形态和颌骨骨缺损区内部结构高度匹配。（2）分别对三种支架模型结构进行有限元分析,分析符合要求。（3）基于布尔运算对支架模型的外部形态同骨缺损区进行匹配。基于CT数据,计算机辅助设计及Mimics三维软件,重建三维模型,利用3D打印技术制造支架实体模型。有限元分析的表明,在同等条件下,立方体结构的支架具有较好的力学性能。

The purpose of this study was to analyze Finite element of jaw bone scaffold materials and the 3D printing model based on CT data, in order to further determine the CT technology and 3D printing technology in the feasibility of building a bone tissue, at the same time, this research discussed the technical problems of build bone scaffold material engineering. CT data of bone defect area was used in 3D building, as to patients with jaw cyst in maxillofacial surgery of Wuhan first hospital, the jaw bone defect area were subjected to CT scan, then the DICOM data was imported into Mimics, and finally jaw defect part were taken for 3D modeling. Pro/E software was employed to design three different internal forms of Scaffold material, such as stents- cube structure, honeycomb structure, and bionic bone structure. Support material load was set at 90 N, poisson＇s ratio was 0.3, with the elastic modulus of 11 Gpa, and ground for fully controlled, then the finite element analysis was carried out on the deformation and stress. The built support structure was imported into Magics to output STL format, and was connected with entity model in 3D printers. The experiment found that： （1） external form of scaffold material modle by 3D type technique match highly with internal jaw defect part. （2） At the same time, the finite element analysis showed that bracket structures were compliant with the requirement. （3） Boolean operations were used to matchthe external form and bone defect. Based on CT data, computer-aided design and Mimics were employeo to rebuild three-dimensional model, 3D printing technology was applied in the preparation of bracket structure. We conclued thata under the same experimental conditions, the structure of the cube stent had better mechanical properties.