再议烧伤瘢痕治疗

Reconsideration of burn scar treatment

由于瘢痕形成的机制尚不完全清楚，迄今没有非常理想的手段预防和治疗烧伤后瘢痕。近年来，在压力治疗、外用硅凝胶、瘢痕内注射皮质激素等常规治疗的基础上，点阵二氧化碳激光治疗、注射抗血管内皮生长因子抗体、自体脂肪移植、注射A型肉毒毒素、放射治疗等多种方法逐渐被用于治疗烧伤瘢痕。根据患者和瘢痕的具体情况，个体化、综合地选用多种方法是非常重要的。此外，有必要继续研究和探讨瘢痕靶向治疗的可能性。

Since the mechanisms of scar formation are not fully understood, at least to date, there is no ideal method to prevent and treat scar after burn. In recent years, on the basis of conventional treatments, such as pressure therapy, external use of silicone gel, and intralesional injections of corticosteroids, the therapeutic approaches of fractional carbon dioxide laser treatlnent, injection of anti-vascular endothelial growth factor antibody, autologous fat transplantation, injection of botulinum toxin A, radiation therapy etc. , have been gradually applied to treat burn scars. It is very important to select various methods individually and comprehensively according to the specific conditions of patients and scars. Meanwhile, it is necessary to continue to study and explore the possibility of targeted therapy in scar management.