《伤寒论》桂枝汤类方应用剂量探讨

Dosage of Guizhi decoction prescriptions in Treatise on Febrile Diseases

《伤寒论》所载经方,源远流长,桂枝汤在全论中化裁较多,作用广泛。桂枝汤类方煎服法多为水七升,微火煮取三升,去滓,温服一升。本文从考古学发现及现代文献研究、古代医家的临床经验、古代文献记载的研究推论、中药煎煮方式等方面进行分析讨论,总结出现代应用桂枝汤类方一两应在6.9~7.8 g。在考虑方剂有效性以及药物使用安全性的前提下,认为在治疗慢性疾病过程中桂枝汤类方中一两实际用量可折算为4.6~5.2 g。

The classical prescriptions contained in the Treatise of Febrile Diseases have a long history, and among them Guizhi decoction prescriptions have been used widely. The routine decocting and administering method of Guizhi decoction prescriptions is adding 7 liters of water, decocting lightly up to 3 liters, removing the scum, and administering 1 liter at a warm temperature. This paper analyzed and discussed the archeological discovery and modern literature research, the clinical experience of ancient physicians, the research inferences of ancient literature records and the method of decoction of traditional Chinese medicine, etc., and concluded that the dosage of one liang（an ancient unit of weight） in Guizhi decoction prescriptions should be about 6.9-7.8 g. Considering the efficacy of prescriptions and the safety of drug use, one liang in Guizhi decoction prescriptions for the treatment of chronic diseases can be converted to 4.6-5.2 g.