ANRIL在肿瘤中作用的研究进展

The reaserch progress of ANRIL associated with tumor

随着医学的不断进步、实验技术的革新和计算机的多功能化,临床可以应用的肿瘤靶向药物越来越多,长链非编码RNA受到广泛关注,ANRIL的作用和生物学功能也得到了深入研究,其在基因的转录翻译、细胞分化、个体发育、遗传及表观遗传等生命活动中具有重要的调控作用。本文即总结国内外ANRIL对肿瘤作用研究的现状,对ANRIL与不同肿瘤的相互关系作一综述。

With the continuous progress of medicine,the innovation of experimental technology and the multi-functionalization of computer,more and more tumor targeting drugs can be used in clinical practice. The long non-coding RNA is widely concerned. The role and biological function of ANRIL have been studied deeply,and it is in the translation of genes,cell differentiation,individual development,genetic and epigenetic life activities have an important regulatory role. This review summarizes the research status of ANRIL on tumor at home and abroad. The relationship between ANRIL and different tumors is reviewed.