血液透析患者并发高磷血症的非疾病性因素研究

A study for non-disease factors correlated with hyperphosphatemia in patients receiving hemodialysis

目的调查和分析慢性肾脏病血液透析治疗患者并发高磷血症的非疾病性因素。方法采用便利抽样法,抽取天津市2所医院的3个血液净化中心的397例慢性肾脏病行血液透析治疗的患者作为研究对象。采用单因素分析血磷与社会人口学因素、相关临床因素、相关知识和行为得分、躯体健康和心理健康得分的关系;采用Logistic回归分析探讨影响血磷水平的因素。结果 Logistic回归分析显示,性别、血液透析龄与血磷独立相关,男性患者和透析龄长者更易发生高磷血症;疾病知识、饮食知识和依从性得分低的患者也容易发生高磷血症。结论临床中应更多关注易发生高磷血症的患者,定期对患者疾病、饮食和服药等相关知识进行测评,加强对患者的健康教育,控制血磷水平。

Objective To analyze the non-disease factors of chronic kidney disease （CKD） hemodialysis patients with hyperphosphmia. Methods A total of 397 patients from three hemodialysis centers were recruited using con- venience sampling from two hospitals in Tianjin. The relationship between the relevant factors：demographic,clinical, scores of relevant knowledge and behavior and self-reports of health status were analyzed. Univariate associations of one-way analysis of variance （ANOVA）,independent samples T-tests and Spearman＇s rank correlation were used to initially select the potential relationship between serum phosphorus and the variables described above. Logistic re- gression was adopted to analyze the independent predictor of hyperphosphatemia. Results The result of logistic re- gression showed that gender,time on hemodialysis,disease knowledge,dietary knowledge and compliance were the independent factors of hyperphosphatemia. Conclusion Given the high costs and mortality of this complex morbidi- ty,increased emphasis upon nursing interventions should be applied to patients who were male,longer hemodialysis treatment durations ,lower knowledge scores of disease and dietary,compliance and attitude.