多索茶碱联合雾化吸入可必特治疗支气管哮喘急性发作的疗效及对肺功能的影响

Efficacy of doxofylline combined with aerosol inhalation of combivent on acute attack of bronchial asthma and its influence on pulmonary function

目的探讨多索茶碱联合雾化吸入可必特治疗支气管哮喘急性发作的疗效及对肺功能的影响。方法将我院收治的支气管哮喘急性发作患者82例随机分为对照组和观察组,每组41例。两组患者均接受基础治疗,对照组在此基础上给予多索茶碱治疗,观察组在对照组的基础上联合可必特雾化吸入治疗。对比两组患者的临床疗效和肺功能改善情况。结果观察组患者的治疗总有效率明显高于对照组(P<0.05)。治疗后,两组患者FEV1、FVC、FEV1/FVC及PEF水平均明显升高,且观察组均高于对照组(P<0.05)。结论在支气管哮喘急性发作患者的治疗中,多索茶碱联合雾化吸入可必特治疗效果理想,治疗后患者肺功能各项指标趋于正常,推荐推广。

Objective To investigate the efficacy of doxofylline combined with aerosol inhalation of combivent on acute attack of bronchial asthma and its influence on pulmonary function. Methods A total of 82 patients with acute attack of bronchial asthma treated in our hospital were randomly divided into control group and observation group, with 41 cases in each group. Both groups received basic treatment, while the control group was given doxofylline on this basis, the observation group was given aerosol inhalation of combivent on the basis of the control group. The clinical efficacy and improvement of pulmonary function were compared between the two groups. Results The total effective rate of treatment in the observation group was significantly higher than that in the control group（P〈 0.05）. After treatment, the levels of FEV1,FVC, FEV1/FVC and PEF in the two groups significantly increased, and those of the observation group were significantly higher than the control group（P〈 0.05）. Conclusion In the treatment of patients with acute attack of bronchial asthma, the doxofylline combined with aerosol inhalation of combivent has an ideal effect, and the indicators of pulmonary function tend to be normal after treatment. It is recommended to promote.