电针联合双氯芬酸钠缓释片治疗膝骨关节炎的临床疗效

Clinical effect of electric acupuncture combined with sodium diclofenac sustained release tablet in the treatment of knee osteoarthritis

目的评估电针联合双氯芬酸钠缓释片治疗膝骨关节炎的临床疗效。方法收集2016年9月至2017年9月就诊的膝骨关节炎患者共100例。按照随机原则将患者分为治疗组(接受双氯芬酸钠缓释片与电针联合治疗)与对照组(接受双氯芬酸钠缓释片治疗),每组50例。两组均接受8周治疗,比较两组患者的治疗效果。结果治疗组的治疗总有效率高于对照组(P<0.05);治疗4周后,治疗组的关节疼痛、关节僵硬及膝关节功能评分均显著下降,且显著低于对照组(P<0.05);治疗8周后,两组患者的关节疼痛、关节僵硬及膝关节功能评分均显著下降,且治疗组显著低于对照组(P<0.05);治疗组患者关节腔积液及滑膜厚度随治疗时间延长逐渐减小(P<0.05);两组不良反应总发生率无统计学差异(P>0.05)。结论电针联合双氯芬酸钠缓释片能够较迅速改善膝骨关节炎患者血液循环,缓解关节腔积液及滑膜增厚,值得临床推广。

Objective To evaluate the clinical effects of electric acupuncture combined with sodium diclofenac sustained release tablet in the treatment of knee osteoarthritis. Methods One hundred cases of patients with knee osteoarthritis treated in our hospital were selected from September 2016 to September 2017. The patients were randomly divided into treatment group（treated with electric acupuncture combined with sodium diclofenac sustained release tablet） and control group（treated with sodium diclofenac sustained release tablet）, with 50 cases in each group. Both groups received treatment for 8 weeks, and the treatment effects in the two groups were compared. Results The total effective rate of treatment in the treatment group was higher than that of the control group（P〈0.05）. After 4 weeks of treatment, the scores of joint pain,joint stiffness and knee joint function in the treatment group significantly decreased, and which were lower than those in the control group（P〈0.05）. After 8 weeks of treatment, the scores of joint pain, joint stiffness and knee joint function in the two groups significantly decreased, and those in the treatment group were lower than the control group（P〈0.05）. The synovial thickness and synovial fluid in the treatment group decreased gradually with the extension of treatment time（P〈0.05）. There was no statistical difference in the total incidences of adverse reactions between the two groups（P〉0.05）. Conclusion Electric acupuncture combined with sodium diclofenac sustained release tablet can rapidly improved blood circulation of patients with knee arthritis, and relieved joint cavity effusion and synovial thickening of patients with knee osteoarthritis, which is worthy of clinical promotion.