地佐辛对下肢骨折患者腰硬联合麻醉术后疼痛有效性的影响

Influence of the Postoperative Pain Efficacy of Dezocine in Patients with Lower Limb Fractures Combined with Spinal Epidural Anesthesia

目的:研究地佐辛对下肢骨折患者腰硬联合麻醉术后疼痛有效性的影响。方法:选择2016年10月～2017年10月在某院进行手术的50例下肢骨折患者,分成研究组和参照组各25例患者,麻醉后给予研究组患者地佐辛,参照组则不做任何处理,评估并对比两组患者术后的疼痛评分以及不良反应发生率。结果:在术后研究组患者的疼痛评分明显低于参照组(P<0.05);研究组患者的不良反应发生率明显低于参照组(P<0.05)。结论:地佐辛能够有效地缓解下肢骨折患者腰硬联合麻醉术后急性疼痛,还能够有效地缓解患者术中、术后的不良反应发生率,临床效果较为显著,应当广泛使用。

Objective To investigate the clinical effect of dexmedetomidine and lumbar spinal anesthesia in the treatment of myomectomy. Methods： 70 patients treated with uterine fibroid surgery in a hospital from May 2017 to Dec 2017 were randomly divided into study group and control group. Propofol combined with lumbar spinal anesthesia（study group） and dexmedetomidine combined with lumbar spinal anesthesia （control group） were used respectively. The effects and adverse reactions of different clinical anesthetic indexes were compared. Results： The heart rate index and sedation score of the study group were significantly higher than those of the control group. The bispectral index of EEG was significantly lower than that of the control group. The anesthetic effect was significantly better than that of the control group. The adverse reaction was significantly lower than that of the control group （ P 〈0.05）. Conclusion： The application of dexmedetomidine combined with lumbar epidural anesthesia in myomectomy can stabilize the vital signs of patients and achieve the expected anesthetic effect, which can control adverse events, adverse reactions,with high safety and outstanding clinical value.