痛风知识教育对2型糖尿病合并高尿酸血症患者血尿酸及血脂水平的影响

Effect of Gout Knowledge Education on Blood Uric Acid and Blood Lipid Level in T2DM Patients with Hyperuricemia

目的:探究2型糖尿病合并高尿酸血症给予痛风知识教育干预对其血尿酸及血脂水平的影响。方法:选取某社区在2013年1月～2017年9月期间500例2型糖尿病患者,根据问卷调查及体检结果将其中54例合并有高尿酸血症患者作为研究对象,随机分成观察组与对照组,每组27例。对照组给予糖尿病知识教育干预,观察组在此基础上给予痛风知识教育干预,比较干预前后血尿酸水平及血脂水平等。结果:干预前两组血尿酸及血脂水平相比,差异无统计学意义(P>0.05);干预后观察组血尿酸水平、TC、TG、LDL-L等血脂指标水平均低于对照组,HDL-L水平高于对照组,差异有统计学意义(P<0.05)。结论:2型糖尿病合并高尿酸血症患者实行痛风知识教育干预,可有效降低血尿酸水平,改善血脂水平,缓解患者症状。

Objective To investigate the effect of gout knowledge education intervention on blood uric acid and blood lipid level in type 2 diabetes mellitus （T2DM） patients with hyperuricemia. Methods： 500 T2DM patients in a community from January 2013 to September 2017 were selected, accordingto the results of questionnaire and health examination,54 cases of T2DM with hyperuricemia were selected and randomly divided into observation group and control group, 27 cases in each group.Control group was given diabetes knowledge education intervention, while observation group was given gout knowledge education intervention based on control group.The levels of uric acid and blood lipid before and after intervention were compared. Results： Before intervention, there was no statistical difference in the levels of uric acid and blood lipid between the two groups （ P 〉0.05）;After intervention, the levels of uric acid, TC, TG, LDL-L in observation group were lower than those in control group, and the level of HDL-L was higher than control group,the difference were statistically significant（ P 〈0.05）. Conclusion： Gout knowledge education intervention in T2DM patients with hyperuricemia can effectively decrease the level of uric acid, improve blood lipid level and relieve patients＇ symptoms.