胆管癌的诊断研究进展

Research Progresses on Diagnosis of Cholangiocarcinoma

胆管癌是起源于胆管上皮的恶性肿瘤,早期缺乏典型的临床症状,而且无特异性指标,早期诊断较困难,待出现梗阻性黄疸时往往已处于中晚期阶段,肿瘤多呈浸润性生长,易发生淋巴结及神经组织转移,预后差。随着影像学技术的不断发展,可对胆管癌进行较完善的临床分期和术前评估。但一些非肿瘤性病变的影像表现与胆管癌相似,仍需结合临床病史、实验室检查等以资鉴别。

Cholangiocarcinoma is a malignant tumor originating from bile duct epithelium.It lacks typical clinical symptoms in the early stage and has no specific markers.It is difficult to diagnose early.It is often in the middle and advanced stage when obstructive jaundice appears.Cholangiocarcinoma is of invasive growth,with metastasis of lymph node and nervous tissues,and its prognosis is poor.The continuous development of imaging examination has contributed to better clinical staging and preoperative assessment of cholangiocarcinoma.However,the imaging features of some non-neoplastic lesions are similar to those of cholangiocarcinoma,which still need to be differentiated by clinical history and laboratory examination.