雷贝拉唑与奥美拉唑治疗反流性食管炎临床效果比较

Comparison of the Clinical Effects of Rabeprazole and Omeprazole in the Treatment of Reflux Esophagitis

目的对比雷贝拉唑与奥美拉唑治疗反流性食管炎临床效果。方法对我院2016年8月至2017年8月间收治的反流性食管炎患者110例进行回顾性分析,根据用药方案不同分为A、B两组,每组各55例。A组采取雷贝拉唑治疗,B组采取奥美拉唑治疗,比较两组患者治疗效果。结果 A组总有效率(96.36%)要明显高于B组(83.64%);治疗后,两组患者症状总积分均有所下降,但研究组症状总积分水平要低于对照组,两组比较差异显著(P<0.05)。结论雷贝拉唑治疗反流性食管炎临床效果较奥美拉唑具有一定优势,可进一步缓解患者症状。

Objective To compare the clinical effects of rabeprazole and omeprazole in the treatment of reflux esophagitis. Methods 110 cases of Reflux Esophagitis Treated in our hospital from August 2016 to August 2017 were retrospectively analyzed. According to the different regimensm,they were divided into two groups A and B, 55 cases in each group. Group A was treated with rabeprazole, group B was treated with omeprazole, and the therapeutic effect of the two groups was compared. Results The total effective rate of group A（96.36%） was significantly higher than that in group B（83.64%）. After treatment, the total score of symptoms in the two groups decreased, but the total symptom score of the study group was lower than that of the control group, and the two groups was significantly different（P〈0.05）. Conclusion The clinical effect of rabeprazole in treating reflux esophagitis is better than omeprazole, and it can further relieve the symptoms of the patient.