自动调节持续气道正压通气强化治疗对老年阻塞性睡眠呼吸暂停低通气综合征患者的疗效

Efficacy of Self-regulated Continuous Positive Airway Pressure Therapy in Obstructive Sleep Apnea-hypopnea Syndrome

目的回顾性分析对老年阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者行自动调节持续气道正压通气强化治疗的临床疗效。方法选择我院2015.8~2017.7收治的50例老年OSAHS患者作为研究对象,所有患者按随机排列表法分为两个组,常规组和治疗组两组,每组各25例,常规组行常规治疗,治疗组患者行自动调节持续气道正压通气强化治疗。观察两组患者治疗前后的呼吸暂停低通气指数(AHI)、夜间平均血氧饱和度(SaO_2mean),夜间最低血氧饱和度(SaO_2min)等情况。结果治疗前两组患者AHI、SaO_2mean、SaO_2min等情况无明显差异,P>0.05;治疗后治疗组AHI指数缩短幅度明显较对照组缩短幅度更大,P<0.05;治疗组治疗后SaO_2mean增加幅度明显较常规组增加幅度更大,治疗组SaO 2min增加幅度明显较常规组增加幅度更大,P<0.05。结论对该疾病患者行自动调节持续气道正压通气强化治疗进行治疗具有明显的治疗效果,值得采用。

Objective To retrospectively analyze the efficacy of self-regulated continuous positive airway pressure therapy in obstructive sleep apnea-hypopnea syndrome（OSAHS）. Methods 50 elderly OSAHS patients treated from August 2015 to July 2017 in our hospital were selected. According to the random number table, the subjects were assigned to two groups, 25 cases each group. The conventional group adopted the conventional therapy; the treatment group adopted the intensive therapy of self-regulated continuous positive airway pressure. The apnea hypoventilation index（AHI）, mean oxygen saturation（SaO_2 mean） and lowest oxygen saturation（SaO_2 min） for two groups were explored. Results Before treatment, the values of AHI, SaO_2 mean and SaO_2 min for two groups were not significantly different（P〉0.05）; after treatment, the declining AHI values in the treatment group were significantly larger than control group（P〈0.05）; after treatment, the increasing SaO_2 mean and SaO_2 min values in the treatment group were larger, with significant difference among groups（P〈0.05）. Conclusion The intensive therapy of selfregulated continuous positive airway pressure has an obvious effect in elderly OSAHS patients. It shall be applied in clinical practice.