左卡尼汀联合生长抑素治疗轻中度急性脂源性胰腺炎的疗效分析

Efficacy of Levocarnitine Combined with Somatostatin in the Treatment of Mild to Moderate Acute Lipoid Pancreatitis

目的探讨左卡尼汀联合生长抑素治疗急性脂源性胰腺炎的疗效分析。方法选择我院消化内科2015年1月至2017年12月确诊为轻中度急性脂源性胰腺炎患者68例,随机分为两组,对照组采用生长抑素治疗,治疗组采用左卡尼汀联合生长抑素治疗,两组其余常规治疗相同。观察两组临床疗效差异。结果治疗组患者症状及腹部深压痛消失时间、血清甘油三酯(TG)下降小于5.65mmol/L时间、平均住院时间,均明显优于对照组(P<0.05)。结论左卡尼汀联合生长抑素治疗急性脂源性胰腺炎的疗效显著,能缩短患者住院时间,具有一定临床意义。

Objective To investigate the efficacy of Levocarnitine combined with somatostatin in the treatment of acute pancreatitis. Methods Sixty-eight patients with mild to moderate acute lipogenic pancreatitis diagnosed in the Department of Gastroenterology from January 2015 to December 2017 were selected. They were randomly divided into two groups. The control group was treated with somatostatin. The treatment group was treated with Levocarnitine combined with somatostatin. The rest of the two groups had the same routine treatment. The difference of clinical efficacy between the two groups was observed. Results In the treatment group, the disappearance time of symptoms and deep deep tenderness, serum triglyceride（TG） decreased by less than 5.65 mmol/L, and the average hospital stay were significantly better than the control group（P〈 0.05）. Conclusion Levocarnitine combined with somatostatin is effective in the treatment of acute pancreatitis, which can shorten the length of hospital stay and has certain clinical significance.