SEPT9基因甲基化检测在结直肠癌早期诊断中的应用

Application of methylation detection of SEPT9 gene in early diagnosis of colorectal cancer

SEPT9基因属于SEPT基因家族中的一员,近年来研究发现结直肠癌细胞中SEPT9基因呈现高度甲基化.检测SEPT9基因甲基化在结直肠癌发生发展中参与的信号通路,分析不同标本类型在SEPT9基因甲基化检测中的应用,比较SEPT9基因甲基化检测方法,可为结直肠癌的早期诊断提供依据.

 SEPT9 gene belongs to a member of SEPT gene family.In recent years,it has been found that SEPT9 gene is highly methylated in colorectal cancer cells.Detecting SEPT9 gene methylation in the development of colorectal cancer,the application of different specimen types for the detection of SEPT9 gene methylation and the development of SEPT9 gene methylation detection methods can provide evidence for early diagnosis of colorectal cancer.