妊娠合并子宫肌瘤对分娩和新生儿的影响

Effects of pregnancy complicated with uterine fibroids on delivery and neonatal status

目的探讨妊娠合并子宫肌瘤对分娩情况、分娩方式及新生儿情况的影响。方法选取2017年2月至2018年2月间山东省立第三医院收治的78例妊娠合并子宫肌瘤的患者作为研究组,另选取同期分娩的78例健康产妇作为对照组。观察并比较两组产妇的分娩方式(剖宫产和阴道助产和阴道分娩)、分娩情况(胎膜早破、先兆流产和胎位异常)及新生儿情况(宫内窘迫、早产和新生儿窒息)。结果研究组先兆流产与胎位异常的发生率均高于对照组,差异均有统计学意义(均P<0.05);两组胎膜早破发生率比较,差异无统计学意义(P>0.05)。研究组阴道分娩率低于对照组,剖宫产率高于对照组,差异均有统计学意义(均P<0.05)。两组阴道助产率比较,差异无统计学意义(P>0.05)。研究组出生孕周及出生体质量均低于对照组,差异有统计学意义(P<0.05),两组新生儿1min Apgar评分与出生身长比较,差异无统计学意义(P>0.05)。结论妊娠合并子宫肌瘤会增加剖宫产概率,且对产妇与新生儿均有不良影响,临床工作者应给予足够的重视,做好产前检查与保健工作,以便保证母儿的健康与安全。

Objective To investigate the effect of pregnancy complicated with uterine fibroids on delivery and neonatal status. Methods Seventy-eight pregnant patients with uterine fibroids who were trea- ted at Shandong Provincial Third Hospital from February 2017 to February 2018 were selected as the study group for the retrospective study. Another 78 healthy pregnant women who were examined and delivered dur- ing the same period at the hospital were selected as the control group. Delivery pattern （ cesarean section, vaginal delivery and vaginal delivery） , childbirth （premature rupture of membranes, threatened abortion, abnormal fetal position）, and neonatal conditions （distressed intrauterine, preterm and neonatal asphyxia） were observed between the two groups. Results The incidence of threatened abortion and abnormal fetal position was higher in the study group than in the control group （ all P 〈 0. 05 ）. There was no significant difference in the incidence of premature rupture of membranes between the two groups （ P 〉 0. 05 ）. The va- ginal delivery rate was lower in the study group than in the control group （P 〈 O. 05 ）. The cesarean section rate was higher in the study group than in the control group （ P 〈 0.05 ）. There was no significant difference in vaginal delivery rate between the two groups （P 〉 0.05 ）. The delivery gestation and quality of life were lowere in the study group than in the control group （P 〈 0. 05）. There was no significant difference in 1 rain Apgar score and birth body length between the two groups （ P 〉 0.05 ）. Conclusion Pregnancy with uter- ine fibroids can increase the probability of cesarean section, and have adverse effects on both mothers and newborns. Clinicians should pay enough attention to prenatal examinations and health care in order to ensure the health of mothers and children Safety.