Amplatzer多孔筛状房间隔缺损封堵器治疗房间隔膨出瘤合并房间隔缺损的初步临床研究

Closure of atrial septal defect with atrial septal aneurysm by amplatzer cribriform occluder

目的评估Amplatzer多孔筛状房间隔缺损封堵器(ACO)治疗房间隔膨出瘤(ASA)合并房间隔缺损的可行性、有效性及安全性。方法 2015年6月至2016年6月我院使用Amplatzer ACO经导管介入封堵ASA合并房间隔缺损的16例成人患者(男2例,女14例),年龄22～58岁,平均(46.23±8.56)岁,观察技术成功率、并发症、残余分流情况,术后6个月随访时复查超声心动图、胸片、心电图。结果 16例患者均封堵成功,技术成功率100%,2例选用25/25mmACO,5例选用30/30mm ACO,9例选用35/35mmACO。手术时间为25～65min,平均(38.67±11.72)min。无手术并发症发生,随访6个月后患者无脑卒中发生,心脏彩超复查无残余分流,无明显心律失常发生。结论对于ASA合并房间隔缺损的患者,采用ACO治疗是一种有效、安全的选择。

Objective To introduce our experience of transcatheter closure of atrial septal defect（ASD） combined with atrial septal aneurysm（ASA）by Amplatzer cribriform occluder（ACO）,and to evaluate its feasibility,efficacy and safety.Methods From June 2015 to June 2016,a total of 16 patients with ASD combined with ASA received transcatheter closure were retrospectively included to observe procedure-related outcomes,such as technical success rate,complications and residual shunt.All patients were followed with echocardiography,chest radiography and electrocardiography postoperatively.Results ACOs were successfully implanted in all 16 patients with ASD combined with ASA,and no procedure-related complications occurred during the operation.The procedural results were encouraging and no complications,such as stroke or residual shunt,occurred during the follow-up.Conclusion ACO might be a better alternative for transcatheter closure in patients with ASD combined with ASA.