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P2X7受体与系统性红斑狼疮关系的研究进展 被引量:3

Research Progress in the Relationship Between P2X7 Receptor and Systemic Lupus Erythematosus
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摘要 系统性红斑狼疮由于发病机制的复杂性且涉及多器官损伤,临床治疗很棘手。在对系统性红斑狼疮的研究中发现,嘌呤受体P2X配体门控性离子通道7(P2X7R)信号通路对系统性红斑狼疮的病情、病程有调控作用,可能通过介导炎性因子的合成和释放参与系统性红斑狼疮的发病。现就P2X7R信号通路及相关炎性细胞因子与系统性红斑狼疮发病关系的研究进展进行综述,为靶向治疗系统性红斑狼疮提供客观依据。
出处 《风湿病与关节炎》 2018年第10期61-65,共5页 Rheumatism and Arthritis
基金 国家自然科学基金(81770915) 潍坊医学院大学生科技创新基金(KX2017015)
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