重症感染患者血磷水平与免疫指标对预后影响

Effect of Blood Phosphorus Level and Immune Index on Prognosis in Patients with Severe Infection

目的探讨重症感染患者血磷与免疫指标水平高低对患者预后的影响。方法选择本院2017年6月～2018年5月ICU入院重症感染患者50例,入住ICU后监测24 h内血磷及免疫指标水平,根据患者血磷水平分为轻度低磷A组、中度低磷B组以及重度低磷C组,分别指血清磷在0.66～0.8 mmol/L、0.32～0.65 mmol/L和<0.32 mmol/L。比较50例患者血磷及免疫指标水平与急性生理及慢性健康评分(APACHEⅡ)之间关系。结果血磷水平高低与免疫指标之间存在正相关,患者血磷及免疫指标越低,APACHEⅡ评分越高,统计学意义显著(P<0.01)。结论重症感染患者免疫指标及早期血磷水平高低均对重症感染患者的病情严重程度及预后的评估具有重要临床指导意义。

Objective To investigate the effect of serum phosphorus and immune levels on the prognosis of patients with severe infection.Methods A total of 50 patients with severe infections admitted to the hospital from June 2017 to May 2018 were enrolled. The blood phosphorus and immune levels were monitored within 24 hours after admission to the ICU.The patients were divided into mild hypophosphate group A according to their blood phosphorus levels.The low-phosphorus B group and the severe low-phosphorus C group were referred to as serum phosphorus at（0.66-0.8）mmol/L,（0.32-0.65）mmol/L,and 〈0.32 mmol/L,respectively.The relationship between serum phosphorus and immune index levels and acute physiological and chronic health scores（APACHE Ⅱ）was compared in 50 patients.Results There was a positive correlation between the level of serum phosphorus and the immune index.The lower the serum phosphorus and immune index, the higher the APACHE Ⅱ score,the statistical significance was significant（P〈0.01）.Conclusion The immune index and early blood phosphorus level in patients with severe infection have important clinical guiding significance for the assessment of the severity and prognosis of patients with severe infection.