清胰汤联合生长抑素治疗急性胰腺炎临床研究

The study on the treatment of acute pancreatitis with the combined growth of Qingyi decoction

目的:探讨清胰汤联合生长抑素治疗急性胰腺炎的临床疗效。方法:选取80例急性胰腺炎患者纳入本次研究,将入选患者均分为对照组及观察组,对照组给予生长抑素治疗,观察组在对照组的基础上给予清胰汤治疗;治疗两个疗程后,评估两组临床疗效,同时观察治疗前后两组患者的临床症状消失时间;观察治疗前后两组化验指标的变化情况;出院前统计两组不良反应发生率、中转手术率及住院时间。结果:观察组临床总有效率为92.50%,对照组为75.00%,观察组临床疗效整体优于对照组(P<0.05)。观察组腹痛、腹胀、无排气、无排便、血淀粉酶升高、WBC升高的消失时间均少于对照组(P<0.05)。治疗后两组血淀粉酶、尿淀粉酶、hs-CRP表达水平均较本组治疗前改善(P<0.05);治疗后观察组各项指标均优于对照组(P<0.05)。观察组不良反应发生率、中转手术率及住院时间均低于对照组(P<0.05)。结论:清胰汤联合生长抑素治疗急性胰腺炎疗效理想,治疗周期短。

Objective： Explore the curative effect of the combined growth inhibition in the treatment of acute pancreatitis. Methods： Selection 80 cases of acute pancreatitis patients, divided into control group and observation group, control group given somatostatin therapy, observation group given Qingyi decoction of pancreas on the basis of control group; after two courses of treatment, the clinical efficacy of the two groups was evaluated, and the clinical symptoms disappeared in the two groups before and after treatment. To observe the changes of the test indexes before and after treatment; the incidence of adverse reactions, the rate of transfer and the length of hospital stay were calculated before discharge. Results： The total clinical efficiency of the observation group was 92.50%, the control group was 75.00%, and the overall clinical efficacy of the observation group was better than that of the control group （ P 〈0.05）. The observation group was less than the control group （ P 〈0.05）, with abdominal pain, abdominal distension, no exhaust, no defecation, increased blood amylase and WBC. The expression levels of blood amylase, urine amylase and hs-crp in the two groups were better than those in the group before treatment （ P 〈0.05）. All the indicators in the observation group were superior to the control group （ P 〈0.05）. The incidence of adverse reactions in the observation group, the rate of transfer operation and the length of hospital stay were all lower than the control group （ P 〈0.05）. Conclusion： The treatment of acute pancreatitis is ideal for the treatment of Qingyi decoction, and the treatment cycle is short.