产时抗生素预防性治疗对B族链球菌感染孕妇的新生儿B族链球菌感染的预防作用

Preventive effect of Antibiotic Prophylactic Therapy on B group Streptococcal Infections in Neonates Infected with group B Streptococcus

目的探讨产时抗生素预防性治疗对B族链球菌感染(GBS)孕妇的新生儿GBS的预防作用。方法选取我院2016年10月—2017年10月收治的GBS感染待分娩孕妇86例为观察对象,以随机数字表法分为观察组和对照组各43例,观察组产时予以青霉素或克林霉素进行预防性治疗,对照组未接受治疗,对两组新生儿GBS感染情况及孕妇发生GBS感染相关疾病进行观察。结果观察组新生儿GBS感染率均低于对照组(P <0. 05),观察组孕妇GBS感染相关疾病发生率低于对照组(P <0. 05)。结论针对GBS感染的孕妇,产时予以抗生素预防性治疗可降低新生儿感染GBS风险,减少产妇GBS感染相关疾病的发生,值得推广。

Objective To investigate the preventive effect of antibiotic prophylactic therapy on GBS in neonates with group B streptococcal infection （GBS）. Methods 86 cases of pregnant women treated with GBS infection in our hospital from October 2016 to October 2017 were selected and divided into 43 cases respectively in the observation group and the control group. The observation group was treated with penicillin or clindamycin and the control group was not treated. The infection of GBS in the two groups of newborns and GBS infection related diseases in pregnant women were observed. Results The incidence of GBS infection in the observation group was lower than that in the control group （ P 〈 0. 05 ） , and the incidence of GBS infection related diseases in the observation group was lower than that in the control group （ P 〈 0. 05 ）. Conclusion For pregnant women with GBS infection, antibiotic prophylactic treatment can reduce the risk of GBS neonatal infection and reduce the incidence of GBS infection related diseases in pregnant women, which is worth promoting.