正清风痛宁缓释片致不良反应的影响因素分析

Influencing Factors of Adverse Drug Reactions Induced by Zhengqing Fengtongning Sustained Release Tablets

目的了解正清风痛宁缓释片致不良反应发生的影响因素。方法收集湖南省内7家三级甲等医院使用了正清风痛宁缓释片的患者4 064例为调查对象。结果正清风痛宁缓释片不良反应发生与性别(女性较高)、年龄段(31～50岁)及联合用药情况相关。结论初步了解了正清风痛宁缓释片不良反应发生情况及影响因素,为进一步研究药品不良反应发生机制提供参考。

Objective To understand the influencing factors of adverse drug reactions（ADR） induced by Zhengqing Fengtongning Sus- tained Release Tablets. Methods A total of 4 064 patients taken Zhengqing Fengtongning Sustained Release Tablets from 7 hospitals in Hunan Province were enrolled for this study. Results ADRs induced by Zhengqing Fengtongning Sustained Release Tablets were associ- ated with gender（female more than male）, age（31 -50 years old） and drugs combination. Conclusion The influencing factors of ADRs induced by Zhengqing Fengtongning Sustained Release Tablets are investigated, which can provide a reference for further study on the mechanism of ADRs.