摘要
目的研讨支原体肺炎患儿通过序贯方法使用阿奇霉素治疗的临床价值。方法选择180例支原体肺炎患儿作随机非盲分组实验,每组90例,Ⅰ组接受阿奇霉素静脉滴注,Ⅱ组通过序贯方法使用阿奇霉素治疗,观察两组的用药情况,并予以比较。结果Ⅱ组相对Ⅰ组在临床药效上明显提升,总有效率达到95.6%,比较有统计学意义(P<0.05)。施治前,两组在IL-4、IL-6及CRP等方面的对比,无统计学意义(P>0.05);施治后,Ⅱ组相对Ⅰ组在上述炎症因子水平上均有明显降低,比较有统计学意义(P<0.05)。结论对小儿支原体肺炎患者使用阿奇霉素序贯治疗是一种可行给药方案,能够明显提升药效,加速清除炎症因子水平,值得推荐。
Objective To study the clinical value of using azithromycin in the sequential treatment of children with mycoplasma pneumonia. Methods Group Ⅰ received intravenous infusion of azithromycin, and group Ⅱ used sequential methods. Azithromycin treatment, observation of drug use in the two groups, and comparison. Results Group Ⅱ showed significant improvement in clinical efficacy compared with group Ⅰ, with a total effective rate of 95.6%, which was statistically significant(P〈0.05). Before treatment, there was no significant difference in the IL-4, IL-6 and CRP between the two groups(P〉0.05). After treatment, the levels of inflammatory cytokines in group Ⅱ were significantly lower than those in group Ⅰ(P〈0.05). Conclusion Sequential treatment with azithromycin in children with mycoplasma pneumonia is a feasible dosing regimen, which can significantly improve the efficacy and accelerate the clearance of inflammatory factors. It is worth recommending.
作者
刘晓宇
LIU Xiao-yu(Nanjing Pukou Hospital of Traditional Chinese Medicine,Nanjing,Jiangsu,211800)
出处
《智慧健康》
2018年第8期67-68,共2页
Smart Healthcare
关键词
小儿支原体肺炎
序贯方法
阿奇霉素
临床价值
Mycoplasma pneumonia in children
Sequential method
Azithromycin
Clinical value