基础胰岛素联合阿卡波糖对比预混胰岛素治疗2型糖尿病疗效和安全性

Effect and Safety of Basal Insulin Combined with Acarbose Compared with Premixed Insulin in Treatment of Type 2 Diabetes

目的在2型糖尿病的治疗过程中分别应用基础胰岛素联合阿卡波糖和预混胰岛素进行治疗,比较治疗效果和安全性。方法在2016年10月到2018年2月从我院选取72例2型糖尿病患者,将其随机分为对照组与观察组各36例,对照组应用预混胰岛素,观察组应用基础胰岛素联合阿卡波糖。结果治疗完成后,两组患者的FBG和餐后血糖水平均有所下降,且观察组患者的下降幅度大于对照组(P<0.05);观察组患者的不良反应发生率明显低于对照组(P<0.05)。结论在2型糖尿病的治疗过程中分别应用基础胰岛素联合阿卡波糖的治疗效果较好,且不良反应的发生率较低。

Objective treating type 2 diabetes with basic insulin combined with acarbose and premixed insulin respectively, compare curative effect and safety. Methods choose 72 cases type 2 diabetes patients in our hospital from October 2016 to February 2018, divide them into the control and observation group randomly,（36 cases in each）. Control group was treated with premixed insulin, and observation group with basic insulin and acarbose. Results after treatment, FBG and postprandial blood glucose levels of two groups were decreased, and decrease of observation group was greater than control group（P0.05）, incidence of adverse reactions of observation group was significantly lower than control group（P0.05）. Conclusion basal insulin combined with acarbose has good effect in treatment of type 2 diabetes, with lowe incidence of adverse reactions.