右美托咪定复合罗哌卡因硬膜外麻醉用于剖宫产术效果观察

Effect Observation of Dexmedetomidine Combined with Ropivacaine Epidural Anesthesia for Cesarean Section

目的观察右美托咪定(DEX)复合罗哌卡因(Rop)在剖宫产术连续硬膜外麻醉(CEA)中的应用效果。方法选取2017年1月至12月在我院产科实施剖宫产术的232例产妇观察麻醉效果,按单盲、随机、前瞻性原则设计分组,分为右美托咪定复合罗哌卡因组(DEX+Rop组)、罗哌卡因组(Rop组),DEX+Rop组118例,Rop组114例;两组的麻醉方案均为CEA,DEX+Rop组的麻醉药物为利多卡因、Rop、DEX,Rop组的麻醉药物为利多卡因、Rop。结果 DEX+Rop组麻醉效果优良率为90.68%,Rop组为80.70%,DEX+Rop组麻醉效果优于Rop组。DEX+Rop组麻醉起效时间为(5.29±0.13)min,DEX组麻醉起效时间为(7.11±0.16)min。结论在剖宫产术CEA中应用DEX复合Rop方案,能缩短麻醉起效时间及显著改善CEA效果。

Objective to observe effect of dexmedetomidine（DEX） combined with ropivacaine（Rop） continuous epidural anesthesia（CEA） for cesarean section. Methods choose 232 cases cesarean section patients in our hospital from January 2017 to December, observe the anesthetic effect. According to single blind, random and prospective principle, divide them into dexmedetomidine combined with ropivacaine group（group DEX＋Rop）, ropivacaine group（group Rop）, 118 cases in group DEX＋Rop, and 114 cases in group Rop. Anesthetic schemes of two groups was CEA both. Anesthetic drugs of group DEX＋Rop were lidocaine, Rop and DEX. Anesthetic drugs in group Rop were lidocaine and Rop. Results excellent and good rate of anesthesia in group DEX＋Rop was 90.68%, better than 80.70% of group Rop. Anesthesia onset time of group DEX＋Rop was（5.29±0.13） min, and that of group DEX was（7.11±0.16） min. Conclusion DEX combined with Rop can shorten anesthesia onset time and improve effect of CEA significantly during CEA of cesarean section.