耳穴贴压法联合补液法治疗妊娠恶阻的临床观察

Clinical observation on auricular-plaster therapy combined with fluid replacement therapy in treatment of hyperemesis gravidarum

目的观察脾胃虚弱型妊娠恶阻病情,总结耳穴贴压联合补液法治疗的临床效果,并探讨其作用机理,以期为以后临床治疗提供参考依据。方法选取2014年1月-2016年3月在该院确诊为脾胃虚弱型妊娠恶阻的210例患者为研究对象,按就诊时间随机分为实验组、对照组、模型组,每组70例。实验组采用耳穴贴压法联合补液治疗法;对照组采用耳穴贴压治疗法;模型组采用补液治疗法。对比分析不同治疗组的治愈率、总有效率及治疗前后的临床症状改善情况,并进行疗效判定。结果实验组治愈率与对照组、模型组相比,差异均有统计学意义(均P<0.05);治疗后,3组患者临床症状积分均有明显改善,与治疗前相比,差异有统计学意义(均P<0.05);且实验组改善更为显著,与对照组、模型组相比,差异均有统计学意义(均P<0.05);1个疗程治疗后,实验组与对照组、模型组治疗后有效率相比,差异均有统计学意义(均P<0.05);两个疗程治疗后,3组比较差异无统计学意义(P>0.05)。结论耳穴贴压法联合补液法治疗脾胃虚弱型妊娠恶阻疗效明显,可有效缩短疗程,提高治愈率。其治病机理可能是通过与经络的联系及神经反馈的调节,起到镇静止呕的作用,从而治疗疾病。

Objective To observe the clinical condition of hyperemesis gravidarum with weakness of the spleen and the stomach,summarize the clinical effect of auricular-plaster therapy combined with fluid replacement therapy,explore the mechanism of action,provide a reference basis for future clinical treatment. Methods From January 2014 to March 2016,210 patients diagnosed as hyperemesis gravidarum with weakness of the spleen and the stomach in Guangxing Hospital were selected and divided into experimental group,control group,and model group according to the admission time,70 patients in each group. The patients in experimental group were treated by auricular-plaster therapy combined with fluid replacement therapy,the patients in control group were treated by auricular-plaster therapy,and the patients in model group were treated by fluid replacement therapy. The cure rates,the total effective rates,and improvements of clinical symptoms after treatment in the three groups were compared and analyzed,and the curative effects were determined. Results There were statistically significant differences in the cure rate between experimental group and the other two groups（ P〈 0. 05）. After treatment,the scores of clinical symptoms in the three groups were improved significantly,compared with before treatment,there were statistically significant differences（ P〈0. 05）,the improvement in experimental group was more significant,compared with the other groups,there were statistically significant differences（ P〈0. 05）. After one course of treatment,there were statistically significant differences in effective rate between experimental group and the other two groups（ P〈0. 05）. After two courses of treatment,there was no statistically significant difference in effective rate among the three groups（ P〉0. 05）. Conclusion The curative effect of auricular-plaster therapy combined with fluid replacement therapy in treatment of hyperemesis gravidarum with weakness of the spleen and the stomach is significant,the therapy can effectively shorten the course of treatment and improve the cure rate,the mechanism may be correlated with sedation and anti-nausea through the connection with main and collateral channels and the regulation of neural feedback,so the disease is cured.