摘要
通过文献整理将胃癌中医证型与基因、蛋白相关性的研究现状进行综述。整理发现,当前研究中以下几种蛋白和基因与胃癌中医证型关系紧密,如MMP-9、TIMP-2、HER-2、RPL23、MDM2、Rb基因、Livin蛋白、VEGF、p53基因、CD151等。研究中存在的问题,如辨证分型不统一、样本量少等。今后研究宜规范胃癌的中医辨证分型,进行大样本、多因素的研究,深入研究胃癌中医证型与基因、蛋白相关性。
In this paper,we reviewed the research progress of correlation between TCM syndromes and genes and proteins in gastric cancer by literature review. It has been found that the following proteins and genes are closely related to the TCM Syndromes of gastric cancer: MMP-9,TIMP-2,HER-2,RPL23,MDM2,Rb,Livin,VEGF,p53,CD151 and so on. However,there are some problems in the study,such as the disunity of the dialectical types and the small amount of samples. In the future,we should focus on the standardization of TCM syndrome differentiation of gastric cancer,and on this basis,conduct a large sample and multi factor study,in order to explore the correlation between TCM Syndrome Types and gene and protein in gastric cancer.
作者
孙春霞
赵普辉
范焕芳
郭娜
李德辉
闫翠环
SUN Chun-xia;ZHAO Pu-hui;FAN Huan-fang;GUO Na;LI De-hui;YAN Cui-huan(Hebei Provincial TCM Hospital,Shijia Zhuang 050000,China;Hebei College of Traditional Chinese Medicine,Shifia Zhuang 050000,China)
出处
《中国中医基础医学杂志》
CAS
CSCD
北大核心
2018年第9期1335-1338,共4页
JOURNAL OF BASIC CHINESE MEDICINE
基金
河北省中医药管理局科研计划项目(2016164)-疏肝健脾和胃方结合综合性心理干预对中晚期胃癌患者的临床疗效观察
关键词
胃癌
证型
基因
蛋白
研究现状
Gastric cancer
Syndrome type
Gene
Protein
Research status