从放化疗的毒副反应逆向思考中药治癌的剂量选择

Careful choose of doses of Chinese drugs for cancer treatment considering the toxic and side effects of radiotherapy and chemotherapy

放疗与化疗是当前治疗癌症的两种主要手段,当各自单独使用时对癌症有一定的疗效,但也存在一定的毒副作用;当联合使用时能够提高疗效,但毒副作用也相应增加。由此逆向思考,中药在治疗癌症的过程中,如使用剂量过小,虽没有毒副作用但也没有疗效,所以需要增大剂量,以提高疗效。但中药的本名是毒药,使用大剂量中药,就是用大毒治病。我们需要在中医整体观念和辨证论治理论指导下,足量、合理、安全地使用中药,"重剂起沉疴",充分发挥中药在癌症治疗中的主动作用,以显示中医在癌症治疗中的主导地位。

Radiotherapy and chemotherapy are the two main methods for the treatment of cancer. When used alone, they have certain toxic and side effects as well as a certain therapeutic effect on cancers. Their combined use can improve the efficacy, but their toxic and side effects also increase. If the dose of Chinese drugs is too small, there are neither the toxic and side effects nor the curative effect. To treat various cancers, it is necessary to increase the dose in order to improve the curative effect. The primary name of traditional Chinese medicine （TCM） is poison. Using large doses of traditional Chinese drugs is a cure with poison for the disease. Under the guidance of the overall concept of TCM and the theory of syndrome differentiation and treatment, Chinese drugs must be used in a sufficient, rational, and safe manner since the different doses have different effects. Heavy agents play an important role in the treatment of cancer. We should give full play to the active role of TCM in the treatment of cancer so as to demonstrate the dominant position of TCM in cancer treatment.