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达沙替尼与伊马替尼治疗慢性髓性白血病患者的临床疗效 被引量:1

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摘要 目的探讨达沙替尼与伊马替尼治疗慢性髓性白血病(CML)患者的临床疗效。方法选取本溪市中心医院2016年1—12月收治的87例CML患者作为研究对象,运用随机法将其分为观察组44例、对照组43例,对照组使用伊马替尼治疗,观察组使用达沙替尼治疗,比较其治疗效果。结果观察组患者的完全细胞遗传学缓解率(CCy R)持续时间、CCy R率均明显优于对照组,差异均有统计学意义(均P<0.05);而两组治疗后完全血液学缓解率(CHR)比较差异无统计学意义(P>0.05)。观察组不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论采用达沙替尼治疗CML患者与伊马替尼相比,前者起效迅速,药物安全性良好,且治疗效果显著,其可作为治疗CML疾病的理想药物。
作者 耿韦韦 冯谦
机构地区 本溪市中心医院
出处 《中国药物经济学》 2018年第7期66-68,共3页 China Journal of Pharmaceutical Economics
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