糖尿病早期肾损伤诊断中尿糖、尿微量白蛋白联合检验的效果分析

Analysis of test results of urine glucose combined with urine microalbumin in the diagnosis of early renal injury in diabetic patients

目的 分析糖尿病早期肾损伤诊断中尿糖、尿微量白蛋白联合检验效果.方法 选取2016年10月至2017年10月本院收治的30例糖尿病早期肾损伤患者为研究组,纳入同期30例健康体检者为对照组.回顾性分析所有研究对象的临床资料及诊断结果,以病理检查结果为金标准,比较两组尿糖、尿微量白蛋白水平以及单一检测和联合检测的准确率情况.结果 研究组尿糖水平为（3.52±1.01）mmol/L,高于对照组的（1.98±0.56）mmol/L,差异有统计学意义（P＜0.05）;研究组尿微量白蛋白水平为（26.71±4.31）mg/L,高于对照组的（16.50±5.13） mg/L,差异有统计学意义（P＜0.05）;联合检测准确率明显高于尿糖和尿微量白蛋白进行单一检测的准确率,差异有统计学意义（P＜0.05）.结论 尿糖、尿微量白蛋白水平均为糖尿病早期肾损伤的主要指标,与单一检测相比,联合检测准确率较高,对于糖尿病早期肾损伤患者的早期诊断和治疗具有重要价值.

Objective To analyze the effect of test results of urine glucose combined with urine microalbumin in the diagnosis of early renal injury in diabetic patients.Methods 30 cases of early diabetic kidney injury patients in our hospital from October 2016 to October 2017 were selected as the study group,and 30 healthy persons during the same period as the control group.Retrospective analysis of c1inical data and diagnosis results of all subjects was performed,with pathological examination results as the gold standard,the levels of urine glucose and urine microalbumin were compared between the two groups,and the accuracy rates of single detection and joint detection.Results The level of urine glucose in the study group was higher than that in the control group [（3.52±1.01） mmol/L vs.（1.98±0.56） mmol/L],with statistically significant difference （P〈0.05）.The level of urine microalbumin in the study group was higher than that in the control group [（26.71±4.31） mg/L vs.（16.50±5.13）mg/L],with statistically significant difference （P〈0.05）.The accuracy rate of joint detection was higher than that of single detection with urine glucose or urine microalbumin,with statistically significant difference （P〈0.05）.Conclusion Urine glucose and urine microalbumin are the main indicators of early renal damage in diabetic patients,compared with single detection,combined detection has higher accuracy,has important value for early diagnosis and treatment of early renal injury in patients with diabetes mellitus.