2014—2015年山东六地市居民植物油中壬基酚暴露风险评估

Risk assessment of nonylphenol exposure in vegetable oil of residents in six cities of Shandong Province in 2014-2015

目的了解山东六地市居民植物油中壬基酚膳食暴露水平,开展风险贡献性评估。方法于2014—2015年,采用分层多阶段整群随机抽样方法抽取山东六地市居民3468人进行膳食调查,称重记账法调查植物油消费量,高效液相色谱-质谱法检测植物油中壬基酚含量,按照《食品安全风险分析——化学危害评估》推荐的点评估方法进行暴露评估。结果山东六地市居民经植物油摄入壬基酚的暴露水平为0~0.44μg/kg,其最高暴露水平远小于丹麦每日耐受摄入量(TDI)5μg/kg;分布点估计最高暴露水平的风险指数为0.088远低于1,且发生此最高暴露水平的概率极低。结论山东六地市居民经植物油摄入壬基酚引起的人体危害性极低。

Objective To investigate the level of nonylphenol dietary exposure in vegetable oils of 6 cities in Shandong Province and to evaluate the contribution of risk. Methods The data of Total Dietary Study and Health Status Survey of Shandong Province and nonylphenol test data were used to evaluate the exposure. A total of 3468 people from 6 cities of Shandong province were selected for food survey by stratified multistage cluster random sampling method in 2014-2015. The consumption of vegetable oil was investigated by weighing and accounting method . Nonylphenol content in dietary samples was detected by high performance liquid chromatography-mass spectrometry （HPLC-MS）. Results The exposure level of nonylphenol in vegetable oil was 0 - 0. 44 μg/kg, and the risk index of the highest point of exposure was 0. 088. Conclusion Risk caused by vegetable oil intake of nonylphenol in Shandong Province 6 city residents is extremely low.