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溃疡性结肠炎患者发生肺栓塞的病例分析

Analysis of pulmonary embolism in patients with ulcerative colitis
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摘要 目的提高对溃疡性结肠炎并发肺栓塞的临床诊疗认识。方法对北京朝阳医院2018年4月22日收治的1例溃疡性结肠炎并发肺栓塞患者的病例进行回顾分析,同时复习文献资料,了解炎症性肠病并发血栓栓塞的机制、影响因素、临床特征及诊疗方案等。结果该例患者入院后泵入普通肝素抗凝治疗,行各项实验室检查及影像学检查。1周后复查心脏超声示左房增大,肺动脉增宽、升主动脉轻度增宽,心包积液(微量),右肺动脉起始处血栓可能,病情较治疗前好转,改为口服利伐沙班抗凝,患者病情逐渐平稳出院。炎症性肠病患者发生动、静脉血栓的概率较高,其机制可能与内皮功能障碍、血小板活化、凝血功能及纤溶功能的异常改变等有关,明确病史、结合临床可以帮助有效辨别和诊疗炎症性肠病并发的肺栓塞等血栓栓塞性疾病。结论肺栓塞是溃疡性结肠炎较易发生的严重血栓栓塞性并发症,炎症性肠病诱导的血栓事件被普遍低估,应当对此类患者进行静脉血栓的评估和干预,以预防静脉血栓的形成。
出处 《中国医刊》 CAS 2018年第10期1163-1166,共4页 Chinese Journal of Medicine
基金 国家重点研发计划精准医学研究(2016YFC0905600)
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