肾性贫血加重中国慢性肾脏病患者经济负担的研究

Research of Economic Burden of CKD Patients with Anemia in China

目的对慢性肾脏疾病(CKD)合并贫血患者及非贫血患者的经济负担进行对比分析,并对贫血治疗用药情况进行描述统计分析。方法本研究数据来源于2015年中国医疗保险研究会(CHIRA)《全国城镇基本医疗保险参保患者药品医疗器械和诊疗项目利用情况调查》,根据患者的诊断或治疗情况进行识别,最终纳入CKD患者共计31 886人。研究中对分类变量指标采用频次和百分比;对连续性数值变量指标采用中位数。结果 CKD合并贫血比CKD非贫血患者全因和因CKD发生年均直接医疗费用中位数分别增加了4倍(23 562元)、12.46倍(9893元),差异均有显著统计学意义(P<0.0001)。结论 CKD合并贫血患者疾病负担显著高于CKD非贫血患者,积极治疗贫血、预防贫血并发症的发生或是降低我国CKD患者经济负担的关键之一。

Objective To estimate the medical costs of CKD patients with and without anemia and to determine the costs for anemia treatment in China. Methods data from Investigation on the utilization of drugs, medical devices, diagnosis and treatment for patients covered by urban residents＇ basic medical insurance, issued by China Medical Insurance Research Association （CHIRA） in 2015, finally 31,886 CKD patients were included according to CKD inclusion ＆ exclusion criteria. Frequency and percentage were used to describe the categorical variables and median was used for continuous numerical vadables. Results The average total annual direct medical cost of CKD patients with anemia were 4 times （￥23,562） higher than those of CKD patients without anemia. The average annual direct medical cost for CKD of anemia patients were 12.46 times （￥9,893） higher than those of non-anemia patients. Conclusion CKD patients with anemia has significantly disease burden than CKD patients without anemia. Actively treat anemia and prevent anemia complications may be the key method to reduce the economic burden of CKD patients in China.